Samandarine
| Code | Size | Price |
|---|
| TAR-T34501-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Samandarine is the main steroidal alkaloid secreted by the fire salamander (Salamandra salamandra). The compound is extremely toxic and causes convulsions, respiratory paralysis, and eventual death.
CAS:
467-51-6
Formula:
C19H31NO2
Molecular Weight:
305.462
Purity:
0.98
SMILES:
C[C@@]12C[C@@H](O)C[C@H]1[C@@H]1CC[C@@H]3C[C@H]4NC[C@H](O4)[C@]3(C)[C@H]1CC2
References
Franke H, Partch R. The chemistry of samandarine model compounds. J Med Chem. 1966 Jul;9(4):643-4. PubMed PMID: 5968049.
Oka K, Hara S. Stereoselective synthesis of samandarine nucleus. Tetrahedron Lett. 1969 May;(24):1987-90. PubMed PMID: 5790176.
Vences M, Sanchez E, Hauswaldt JS, Eikelmann D, Rodr?guez A, Carranza S, Donaire D, Gehara M, Helfer V, L?tters S, Werner P, Schulz S, Steinfartz S. Nuclear and mitochondrial multilocus phylogeny and survey of alkaloid content in true salamanders of the genus Salamandra (Salamandridae). Mol Phylogenet Evol. 2014 Apr;73:208-16. doi: 10.1016/j.ympev.2013.12.009. Epub 2014 Jan 8. PubMed PMID: 24412216.
Mebs D, Pogoda W. Variability of alkaloids in the skin secretion of the European fire salamander (Salamandra salamadra terrestris). Toxicon. 2005 Apr;45(5):603-6. PubMed PMID: 15777956.