Samandarine

Product Code:

TAR-T34501

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

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Code	Size	Price

TAR-T34501-5mg

5mg

£850.00

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Quantity:

Prices exclude any Taxes / VAT

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Further Information

Bioactivity:

Samandarine is the main steroidal alkaloid secreted by the fire salamander (Salamandra salamandra). The compound is extremely toxic and causes convulsions, respiratory paralysis, and eventual death.

CAS:

467-51-6

Formula:

C19H31NO2

Molecular Weight:

305.462

Purity:

0.98

SMILES:

C[C@@]12C[C@@H](O)C[C@H]1[C@@H]1CC[C@@H]3C[C@H]4NC[C@H](O4)[C@]3(C)[C@H]1CC2

Documents

References

Franke H, Partch R. The chemistry of samandarine model compounds. J Med Chem. 1966 Jul;9(4):643-4. PubMed PMID: 5968049. Oka K, Hara S. Stereoselective synthesis of samandarine nucleus. Tetrahedron Lett. 1969 May;(24):1987-90. PubMed PMID: 5790176. Vences M, Sanchez E, Hauswaldt JS, Eikelmann D, Rodr?guez A, Carranza S, Donaire D, Gehara M, Helfer V, L?tters S, Werner P, Schulz S, Steinfartz S. Nuclear and mitochondrial multilocus phylogeny and survey of alkaloid content in true salamanders of the genus Salamandra (Salamandridae). Mol Phylogenet Evol. 2014 Apr;73:208-16. doi: 10.1016/j.ympev.2013.12.009. Epub 2014 Jan 8. PubMed PMID: 24412216. Mebs D, Pogoda W. Variability of alkaloids in the skin secretion of the European fire salamander (Salamandra salamadra terrestris). Toxicon. 2005 Apr;45(5):603-6. PubMed PMID: 15777956.