Saprisartan
| Code | Size | Price |
|---|
| TAR-T34518-5mg | 5mg | £1,653.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34518-50mg | 50mg | £3,267.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34518-100mg | 100mg | £4,488.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Saprisartan (GR-138950, GR-138950X) is an AT1 receptor antagonist used for the treatment of heart failure and blood pressure.
CAS:
146623-69-0
Formula:
C25H22BrF3N4O4S
Molecular Weight:
611.43
Purity:
0.98
SMILES:
CCc1nc(C2CC2)c(C(N)=O)n1Cc1ccc2oc(c(Br)c2c1)-c1ccccc1NS(=O)(=O)C(F)(F)F
References
Charlton ST, Davis SS, Illum L. Nasal administration of an angiotensin antagonist in the rat model: effect of bioadhesive formulations on the distribution of drugs to the systemic and central nervous systems. Int J Pharm. 2007 Jun 29;338(1-2):94-103. Epub 2007 Feb 3. PubMed PMID: 17337137.
Forhead AJ, Jellyman JK, Gillham K, Ward JW, Blache D, Fowden AL. Renal growth retardation following angiotensin II type 1 (AT?) receptor antagonism is associated with increased AT? receptor protein in fetal sheep. J Endocrinol. 2011 Feb;208(2):137-45. doi: 10.1677/JOE-10-0360. Epub 2010 Nov 22. PubMed PMID: 21097994.
Charlton ST, Davis SS, Illum L. Evaluation of bioadhesive polymers as delivery systems for nose to brain delivery: in vitro characterisation studies. J Control Release. 2007 Apr 2;118(2):225-34. Epub 2006 Dec 23. PubMed PMID: 17261340.
Charlton ST, Davis SS, Illum L. Evaluation of effect of ephedrine on the transport of drugs from the nasal cavity to the systemic circulation and the central nervous system. J Drug Target. 2007 Jun;15(5):370-7. PubMed PMID: 17541846.