Sarcophine
| Code | Size | Price |
|---|
| TAR-T34525-5mg | 5mg | £395.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Sarcophine is a natural cembranoid from the Red Sea soft coral Sarcophyton glaucum.
CAS:
55038-27-2
Formula:
C20H28O3
Molecular Weight:
316.441
Purity:
0.98
SMILES:
CC1=C2CCC(C)=C/CCC3(C)OC3CCC(C)=CC2OC1=O
References
Hassan HM, Sallam AA, Mohammed R, Hifnawy MS, Youssef DT, El Sayed KA. Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors. Bioorg Med Chem. 2011 Aug 15;19(16):4928-34. doi: 10.1016/j.bmc.2011.06.060. Epub 2011 Jun 28. PubMed PMID: 21775154.
Szymanski PT, Ahmed SA, Radwan MM, Khalifa SI, Fahmy H. Evaluation of the anti-melanoma activities of sarcophine, (+)-7alpha,8beta-dihydroxydeepoxysarcophine and sarcophytolide from the Red Sea soft coral Sarcophyton glaucum. Nat Prod Commun. 2014 Feb;9(2):151-4. PubMed PMID: 24689276.
Szymanski PT, Ahmed SA, Khalifa S, Tokuda H, Ichiishi E, Iida A, Suzuki N, Fahmy H. Chemopreventive effect of sarcophine-diol on NOR-1-induced TPA-promoted skin carcinogenesis in female HOS:HR-1 mice. Nat Prod Commun. 2013 Feb;8(2):153-4. PubMed PMID: 23513714.
Szymanski PT, Kuppast B, Ahmed SA, Khalifa S, Fahmy H. Sarcophine-diol, a skin cancer chemopreventive agent, inhibits proliferation and stimulates apoptosis in mouse melanoma B??F?? cell line. Mar Drugs. 2012 Jan;10(1):1-19. doi: 10.3390/md10010001. Epub 2011 Dec 22. PubMed PMID: 22363217; PubMed Central PMCID: PMC3280529.