Satratoxin G
| Code | Size | Price |
|---|
| TAR-T34535-5mg | 5mg | £1,458.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Satratoxin G is a trichothecene mycotoxin of Stachybotrys chartarum and has been shown to selectively induces apoptosis in olfactory sensory neurons (OSNs) of the nose and brain.
CAS:
53126-63-9
Formula:
C29H36O10
Molecular Weight:
544.597
Purity:
0.98
SMILES:
C[C@@H](O)[C@@]12OCC[C@]3(O[C@@H]3C(=O)OC[C@]34CCC(C)=C[C@@H]3O[C@@H]3C[C@H](OC(=O)C=C/C=C1)[C@]4(C)[C@@]31CO1)[C@H]2O
References
Amuzie CJ, Islam Z, Kim JK, Seo JH, Pestka JJ. Kinetics of satratoxin g tissue distribution and excretion following intranasal exposure in the mouse. Toxicol Sci. 2010 Aug;116(2):433-40. doi: 10.1093/toxsci/kfq142. Epub 2010 May 13. PubMed PMID: 20466779; PubMed Central PMCID: PMC2909734.
Wu W, Zhou HR, Pan X, Pestka JJ. Comparison of Anorectic Potencies of the Trichothecenes T-2 Toxin, HT-2 Toxin and Satratoxin G to the Ipecac Alkaloid Emetine. Toxicol Rep. 2015;2:238-251. PubMed PMID: 25932382; PubMed Central PMCID: PMC4410735.
Jia C, Sangsiri S, Belock B, Iqbal TR, Pestka JJ, Hegg CC. ATP mediates neuroprotective and neuroproliferative effects in mouse olfactory epithelium following exposure to satratoxin G in vitro and in vivo. Toxicol Sci. 2011 Nov;124(1):169-78. doi: 10.1093/toxsci/kfr213. Epub 2011 Aug 24. PubMed PMID: 21865290; PubMed Central PMCID: PMC3196654.
Carey SA, Plopper CG, Hyde DM, Islam Z, Pestka JJ, Harkema JR. Satratoxin-G from the black mold Stachybotrys chartarum induces rhinitis and apoptosis of olfactory sensory neurons in the nasal airways of rhesus monkeys. Toxicol Pathol. 2012 Aug;40(6):887-98. doi: 10.1177/0192623312444028. Epub 2012 May 2. PubMed PMID: 22552393.