SC 4453
| Code | Size | Price |
|---|
| TAR-T34554-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SC 4453 is a digoxin analog and a cardiac glycoside derivative.
CAS:
59712-21-9
Formula:
C41H64N2O12
Molecular Weight:
776.965
Purity:
0.98
SMILES:
[H][C@]12CC[C@]3([H])[C@@]([H])(C[C@H](O)[C@]4(C)[C@@H](CC[C@]34O)c3ccnnc3)[C@@]1(C)CC[C@H](C2)O[C@H]1C[C@H](O)[C@H](O[C@@H]2C[C@H](O)[C@H](O[C@H]3C[C@H](O)[C@@H](O)[C@H](C)O3)[C@H](C)O2)[C@@H](C)O1
References
Randimbivololona F, Lesne M. Importance of the urinary excretion in the total elimination of SC4453 in the guinea-pig. J Pharmacol. 1984 Apr-Jun;15(2):199-208. PubMed PMID: 6738077.
Gupta RS, Chopra A. Cross-resistance and biochemical studies with two classes of HeLa cell mutants resistant to cardiac glycosides. The unusual behavior of cardenolide SC4453. J Biol Chem. 1985 Jun 10;260(11):6843-50. PubMed PMID: 2987235.
Randimbivololona F, Lesne M. Intestinal absorption of SC4453 in the guinea-pig. Arch Int Pharmacodyn Ther. 1982 Dec;260(2):296-8. PubMed PMID: 7165435.
Randimbivololona F. Distribution of SC-4453, a new semi-synthetic derivative of digoxin, following an infusion preceded by an i.v. loading dose in the guinea-pig. Binding to plasma proteins. Eur J Drug Metab Pharmacokinet. 1988 Jan-Mar;13(1):19-22. PubMed PMID: 3396609.