Sekdel sequence
Code | Size | Price |
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TAR-T34601-5mg | 5mg | £1,251.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T34601-50mg | 50mg | £2,464.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T34601-100mg | 100mg | £3,283.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Sekdel sequence, as a signal, leads to retention of at least two proteins in the endoplasmic reticulum of animal cells.
CAS:
123924-38-9
Formula:
C29H49N7O14
Molecular Weight:
719.746
Purity:
0.98
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CO)C(O)=O
References
Biocca S, Tafani M, Cattaneo A. Assembled IgG molecules are exported from the endoplasmic reticulum in myeloma cells despite the retention signal SEKDEL. Biochem Biophys Res Commun. 1998 May 19;246(2):518-23. PubMed PMID: 9610394.
zu Putlitz J, Skerra A, Wands JR. Intracellular expression of a cloned antibody fragment interferes with hepatitis B virus surface antigen secretion. Biochem Biophys Res Commun. 1999 Feb 24;255(3):785-91. PubMed PMID: 10049788.
Kim YS, Kim MY, Kim TG, Yang MS. Expression and assembly of cholera toxin B subunit (CTB) in transgenic carrot (Daucus carota L.). Mol Biotechnol. 2009 Jan;41(1):8-14. doi: 10.1007/s12033-008-9086-z. Epub 2008 Jul 19. PubMed PMID: 18642102.
Zagouras P, Rose JK. Carboxy-terminal SEKDEL sequences retard but do not retain two secretory proteins in the endoplasmic reticulum. J Cell Biol. 1989 Dec;109(6 Pt 1):2633-40. PubMed PMID: 2592401; PubMed Central PMCID: PMC2115906.