Sinitrodil
Code | Size | Price |
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TAR-T34648-1mg | 1mg | £185.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T34648-5mg | 5mg | £352.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
TAR-T34648-1mL | 1 mL * 10 mM (in DMSO) | £410.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T34648-10mg | 10mg | £496.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T34648-25mg | 25mg | £760.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T34648-50mg | 50mg | £1,018.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T34648-100mg | 100mg | £1,348.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T34648-500mg | 500mg | £2,633.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Sinitrodil is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris
CAS:
143248-63-9
Formula:
C10H10N2O5
Molecular Weight:
238.199
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
[O-][N+](=O)OCCN1COc2ccccc2C1=O
Target:
Guanylate cyclase
References
Monzani MV, et al. Pharmacokinetics of ITF 296 (Sinitrodil) a novel organic nitrate, in healthy volunteers. Eur J Pharm Sci. 1999 Feb;7(3):179-84. PubMed PMID: 9845803.
Khattar RS, et al. Safety, tolerability, and antiischaemic efficacy of ITF-296, a nitric oxide donor, in patients with chronic stable angina. J Cardiovasc Pharmacol. 1998 Aug;32(2):295-9.
Van Bortel LM, et al. Is it possible to develop drugs that act more selectively on large arteries? J Hypertens. 1999 May;17(5):701-5.
Minghetti P, et al. In vitro skin permeation of Sinitrodil, a member of a new class of nitrovasodilator drugs. Eur J Pharm Sci. 1999 Feb;7(3):231-6.