SLP7111228
Code | Size | Price |
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TAR-T34658-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
SLP7111228 is an effective and selective SphK1 inhibitor (Ki = 48 nM).
CAS:
1449765-82-5
Formula:
C22H33N5O
Molecular Weight:
383.54
Purity:
0.98
SMILES:
CCCCCCCCc1ccc(cc1)-c1noc(C[C@@H]2CCCN2C(N)=N)n1
References
Patwardhan NN, Morris EA, Kharel Y, Raje MR, Gao M, Tomsig JL, Lynch KR, Santos WL. Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors. J Med Chem. 2015 Feb 26;58(4):1879-99. doi: 10.1021/jm501760d. Epub 2015 Feb 13. PubMed PMID: 25643074; PubMed Central PMCID: PMC4557804.