Sonoflora 1
| Code | Size | Price |
|---|
| TAR-T34686-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Sonoflora 1, also known as SF1, a PDT photosensitivizer. Chemically, SF1 is an analog of chlorophyll in that its macrocycle backbone is porphyrin-based and the center of the porphyrin ring consists of a metal ion. Preclinical studies showed that SF1 had very high sonodynamic as well as photodynamic activity. The clinically tested results demonstrated positive therapeutic effects for treating patients with advanced refractory breast cancers that had failed to respond to conventional chemotherapy.
CAS:
1609250-37-4
Formula:
C38H39N6Na3O10Sn
Molecular Weight:
927.441
Purity:
0.98
SMILES:
CCC1=C(C)C2=NC1=C/c1c(C)c(C(=O)O[Na])c3C(CC(=O)NCC(=O)NCC(=O)O[Na])=C4/N=C(/C=c5/c(C)c(C=C)c(=C2)n5[Sn--]([OH+])([OH+])n13)[C@@H](C)[C@@H]4CCC(=O)O[Na]
References
Wang X, Zhang W, Xu Z, Luo Y, Mitchell D, Moss RW. Sonodynamic and photodynamic therapy in advanced breast carcinoma: a report of 3 cases. Integr Cancer Ther. 2009 Sep;8(3):283-7. PubMed PMID: 19815599.