SP203
| Code | Size | Price |
|---|
| TAR-T34688-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34688-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34688-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SP203 is a radioligand for brain metabotropic glutamate receptor imaging.
CAS:
945933-41-5
Formula:
C13H6F2N2S
Molecular Weight:
260.26
Purity:
0.98
SMILES:
FCc1nc(cs1)C#Cc1cc(F)cc(c1)C#N
References
Kimura Y, Sim?on FG, Zoghbi SS, Zhang Y, Hatazawa J, Pike VW, Innis RB, Fujita M. Quantification of metabotropic glutamate subtype 5 receptors in the brain by an equilibrium method using 18F-SP203. Neuroimage. 2012 Feb 1;59(3):2124-30. doi: 10.1016/j.neuroimage.2011.10.028. Epub 2011 Oct 19. PubMed PMID: 22032949; PubMed Central PMCID: PMC3254783.
Kimura Y, Sim?on FG, Hatazawa J, Mozley PD, Pike VW, Innis RB, Fujita M. Biodistribution and radiation dosimetry of a positron emission tomographic ligand, 18F-SP203, to image metabotropic glutamate subtype 5 receptors in humans. Eur J Nucl Med Mol Imaging. 2010 Oct;37(10):1943-9. doi: 10.1007/s00259-010-1447-8. Epub 2010 Jun 29. PubMed PMID: 20585776; PubMed Central PMCID: PMC3207261.
Lohith TG, Tsujikawa T, Sim?on FG, Veronese M, Zoghbi SS, Lyoo CH, Kimura Y, Morse CL, Pike VW, Fujita M, Innis RB. Comparison of two PET radioligands, [(11)C]FPEB and [(11)C]SP203, for quantification of metabotropic glutamate receptor 5 in human brain. J Cereb Blood Flow Metab. 2016 Jan 1:271678X16668891. doi: 10.1177/0271678X16668891. [Epub ahead of print] PubMed PMID: 27629098.
Sim?on FG, Liow JS, Zhang Y, Hong J, Gladding RL, Zoghbi SS, Innis RB, Pike VW. Synthesis and characterization in monkey of [11C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors. Eur J Nucl Med Mol Imaging. 2012 Dec;39(12):1949-58. doi: 10.1007/s00259-012-2205-x. Epub 2012 Aug 11. PubMed PMID: 22885775.