S-Palmitoyl cysteine
Code | Size | Price |
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TAR-T34689-5mg | 5mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
S-Palmitoyl cysteine is an important dynamic post-translational modification of cysteine residues within proteins.
CAS:
114507-35-6
Formula:
C19H37NO3S
Molecular Weight:
359.57
Purity:
0.98
SMILES:
CCCCCCCCCCCCCCCC(=O)SC[C@H](N)C(O)=O
References
Dunphy JT, Schroeder H, Leventis R, Greentree WK, Knudsen JK, Silvius JR, Linder ME. Differential effects of acyl-CoA binding protein on enzymatic and non-enzymatic thioacylation of protein and peptide substrates. Biochim Biophys Acta. 2000 May 31;1485(2-3):185-98. PubMed PMID: 10832099.
Ji Y, Bachschmid MM, Costello CE, Lin C. S- to N-Palmitoyl Transfer During Proteomic Sample Preparation. J Am Soc Mass Spectrom. 2016 Apr;27(4):677-85. doi: 10.1007/s13361-015-1319-3. Epub 2016 Jan 4. PubMed PMID: 26729453; PubMed Central PMCID: PMC4794353.
Doubravska L, Krausova M, Gradl D, Vojtechova M, Tumova L, Lukas J, Valenta T, Pospichalova V, Fafilek B, Plachy J, Sebesta O, Korinek V. Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling. Cell Signal. 2011 May;23(5):837-48. doi: 10.1016/j.cellsig.2011.01.007. Epub 2011 Jan 16. PubMed PMID: 21244856.
Hurst CH, Turnbull D, Plain F, Fuller W, Hemsley PA. Maleimide scavenging enhances determination of protein S-palmitoylation state in acyl-exchange methods. Biotechniques. 2017 Feb 1;62(2):69-75. doi: 10.2144/000114516. PubMed PMID: 28193150; PubMed Central PMCID: PMC5400063.