Sphaeropsidin A
| Code | Size | Price |
|---|
| TAR-T34691-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Sphaeropsidin A is the main phytotoxin produced by Diplodia cupressi.
CAS:
38991-80-9
Formula:
C20H26O5
Molecular Weight:
346.423
Purity:
0.98
SMILES:
[H][C@@]12[C@]3(O)OC(=O)[C@@]1(CCCC2(C)C)[C@@]1(O)CC[C@](C)(C=C)C=C1C3=O
References
Cimmino A, Fern?ndez-Aparicio M, Andolfi A, Basso S, Rubiales D, Evidente A. Effect of fungal and plant metabolites on broomrapes (Orobanche and Phelipanche spp.) seed germination and radicle growth. J Agric Food Chem. 2014 Oct 29;62(43):10485-92. doi: 10.1021/jf504609w. Epub 2014 Oct 16. PubMed PMID: 25272312.
Cimmino A, Andolfi A, Avolio F, Ali A, Tabanca N, Khan IA, Evidente A. Cyclopaldic acid, seiridin, and sphaeropsidin A as fungal phytotoxins, and larvicidal and biting deterrents against Aedes aegypti (Diptera: Culicidae): structure-activity relationships. Chem Biodivers. 2013 Jul;10(7):1239-51. doi: 10.1002/cbdv.201200358. Erratum in: Chem Biodivers. 2013 Dec;10(12):2302. PubMed PMID: 23847068.
Wang XN, Bashyal BP, Wijeratne EM, U'Ren JM, Liu MX, Gunatilaka MK, Arnold AE, Gunatilaka AA. Smardaesidins A-G, isopimarane and 20-nor-isopimarane diterpenoids from Smardaea sp., a fungal endophyte of the moss Ceratodon purpureus. J Nat Prod. 2011 Oct 28;74(10):2052-61. doi: 10.1021/np2000864. Epub 2011 Oct 14. PubMed PMID: 21999655; PubMed Central PMCID: PMC3371368.
Mathieu V, Chant?me A, Lefranc F, Cimmino A, Miklos W, Paulitschke V, Mohr T, Maddau L, Kornienko A, Berger W, Vandier C, Evidente A, Delpire E, Kiss R. Sphaeropsidin A shows promising activity against drug-resistant cancer cells by targeting regulatory volume increase. Cell Mol Life Sci. 2015 Oct;72(19):3731-46. doi: 10.1007/s00018-015-1902-6. Epub 2015 Apr 14. PubMed PMID: 25868554; PubMed Central PMCID: PMC4943577.