SR 42128
| Code | Size | Price |
|---|
| TAR-T34704-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SR 42128 is arginine salt.
CAS:
98092-14-9
Formula:
C39H65N5O9
Molecular Weight:
747.975
Purity:
0.98
SMILES:
CC[C@@H](C[C@H](N[C@@H](CC(C)C)C(O)CC(=O)NC(C)C(=O)NC(CC(C)C)[C@@H](O)CC(O)=O)C(N)=O)C(=O)[C@H](Cc1ccccc1)NC(=O)CC(C)C
References
Cumin F, Nisato D, Gagnol JP, Corvol P. A potent radiolabeled human renin inhibitor, [3H]SR42128: enzymatic, kinetic, and binding studies to renin and other aspartic proteases. Biochemistry. 1987 Dec 1;26(24):7615-21. PubMed PMID: 3322402.
Chansel D, Dussaule JC, Ardaillou N, Ardaillou R. Identification and regulation of renin in human cultured mesangial cells. Am J Physiol. 1987 Jan;252(1 Pt 2):F32-8. PubMed PMID: 3544867.
Delie F, Couvreur P, Nisato D, Michel JB, Puisieux F, Letourneux Y. Synthesis and in vitro study of a diglyceride prodrug of a peptide. Pharm Res. 1994 Aug;11(8):1082-7. PubMed PMID: 7971705.
Gougat J, Canat S, Lacour C, Cazaubon C, Gagnol J, Nisato D. [Increase in plasma levels of active and inactive renin after inhibition of renin activity by SR 42128 in conscious Macaca monkeys]. Arch Mal Coeur Vaiss. 1987 Jun;80(6):875-8. French. PubMed PMID: 3116988.