Stichoposide
| Code | Size | Price |
|---|
| TAR-T34720-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Stichoposide is a triterpene glycoside.
CAS:
37341-37-0
Formula:
C43H69O14
Molecular Weight:
810.011
Purity:
0.98
SMILES:
[H][C@]12CC[C@]34[C@H](CC[C]3(C)(OC4=O)C1=CC[C@@]1([H])C(C)(C)[C@H](CC[C@]21C)O[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@H](C)[C@@H](O)[C@H](O)[C@H]1O)[C@@](C)(O)CC(CC(C)C)OC(C)=O
References
Yun SH, Park ES, Shin SW, Ju MH, Han JY, Jeong JS, Kim SH, Stonik VA, Kwak JY, Park JI. By activating Fas/ceramide synthase 6/p38 kinase in lipid rafts, stichoposide D inhibits growth of leukemia xenografts. Oncotarget. 2015 Sep 29;6(29):27596-612. doi: 10.18632/oncotarget.4820. PubMed PMID: 26318294; PubMed Central PMCID: PMC4695011.
Park JI, Bae HR, Kim CG, Stonik VA, Kwak JY. Relationships between chemical structures and functions of triterpene glycosides isolated from sea cucumbers. Front Chem. 2014 Sep 9;2:77. doi: 10.3389/fchem.2014.00077. eCollection 2014. Review. Erratum in: Front Chem. 2014;2:103. PubMed PMID: 25250309; PubMed Central PMCID: PMC4159031.
Aminin DL, Shentsova EB, Anisimov MM, Kuznetsova TA. [Spectrophotometric determination of the stichoposide A from the holothurian Stichopus japonicus S]. Antibiotiki. 1981 Aug;26(8):585-9. Russian. PubMed PMID: 7294749.
Yun SH, Park ES, Shin SW, Na YW, Han JY, Jeong JS, Shastina VV, Stonik VA, Park JI, Kwak JY. Stichoposide C induces apoptosis through the generation of ceramide in leukemia and colorectal cancer cells and shows in vivo antitumor activity. Clin Cancer Res. 2012 Nov 1;18(21):5934-48. doi: 10.1158/1078-0432.CCR-12-0655. PubMed PMID: 23132899.