T-808
| Code | Size | Price |
|---|
| TAR-T34766-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.
CAS:
1320211-61-7
Formula:
C17H19FN4
Molecular Weight:
298.365
Purity:
0.98
SMILES:
FCCC1CCN(CC1)c1ccn2c(nc3ccccc23)n1
References
Chien DT, Szardenings AK, Bahri S, Walsh JC, Mu F, Xia C, Shankle WR, Lerner AJ, Su MY, Elizarov A, Kolb HC. Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808. J Alzheimers Dis. 2014;38(1):171-84. doi: 10.3233/JAD-130098. PubMed PMID: 23948934.
Honer M, Gobbi L, Knust H, Kuwabara H, Muri D, Koerner M, Valentine H, Dannals RF, Wong DF, Borroni E. Preclinical Evaluation of (18)F-RO6958948, (11)C-RO6931643, and (11)C-RO6924963 as Novel PET Radiotracers for Imaging Tau Aggregates in Alzheimer Disease. J Nucl Med. 2018 Apr;59(4):675-681. doi: 10.2967/jnumed.117.196741. Epub 2017 Sep 28. PubMed PMID: 28970331; PubMed Central PMCID: PMC5932750.
Gao M, Wang M, Zheng QH. Concise and high-yield synthesis of T808 and T808P for radiosynthesis of [(18)F]-T808, a PET tau tracer for Alzheimer's disease. Bioorg Med Chem Lett. 2014 Jan 1;24(1):254-7. doi: 10.1016/j.bmcl.2013.11.025. Epub 2013 Nov 20. PubMed PMID: 24309505.
Declercq L, Celen S, Lecina J, Ahamed M, Tousseyn T, Moechars D, Alcazar J, Ariza M, Fierens K, Bottelbergs A, Mari?n J, Vandenberghe R, Andres IJ, Van Laere K, Verbruggen A, Bormans G. Comparison of New Tau PET-Tracer Candidates With [18F]T808 and [18F]T807. Mol Imaging. 2016 Jan 27;15. pii: 1536012115624920. doi: 10.1177/1536012115624920. Print 2016. PubMed PMID: 27030397; PubMed Central PMCID: PMC5470083.