Talampicillin

TargetMol
Product Code: TAR-T34776
Supplier: TargetMol
CodeSizePrice
TAR-T34776-5mg5mg£850.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Further Information

Bioactivity:
Talampicillin is an ester of Ampicillin. It is hydrolyzed upon absorption to release ampicillin. It is well absorbed from the gastrointestinal tract resulting in a greater bioavailability of ampicillin than can be achieved with equivalent doses of ampicillin. It is used in the treatment and prophylaxis of urinary tract infection in children.
CAS:
47747-56-8
Formula:
C24H23N3O6S
Molecular Weight:
481.52
Purity:
0.98
SMILES:
[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C(N)c1ccccc1)C(=O)OC1OC(=O)c2ccccc12

References

Nguyen NA, Mortada LM, Notari RE. Potential improvement in the shelf life of parenterals using the prodrug approach: bacampicillin and talampicillin hydrolysis kinetics and utilization time. Pharm Res. 1988 May;5(5):288-96. PubMed PMID: 3244638. Akimoto Y, Nishimura H, Komiya M, Kaneko K, Fujii A, Tamura T. Ampicillin concentrations in human dental granuloma after a single oral administration of talampicillin. Antimicrob Agents Chemother. 1988 Apr;32(4):566-7. PubMed PMID: 3377465; PubMed Central PMCID: PMC172221. Smellie JM, Gr?neberg RN, Bantock HM, Katz G. Talampicillin in the treatment and prophylaxis of urinary tract infection in children. Chemotherapy. 1982;28(3):218-23. PubMed PMID: 6980099.