Talaporfin free acid
| Code | Size | Price |
|---|
| TAR-T34777-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Talaporfin, an effective tumor localizer, can produce the selective degradation of tumor tissue following light exposure.
CAS:
110230-98-3
Formula:
C38H41N5O9
Molecular Weight:
711.772
Purity:
0.98
SMILES:
CCc1c(C)c2cc3[nH]c(cc4nc([C@@H](CCC(O)=O)[C@@H]4C)c(CC(=O)N[C@@H](CC(O)=O)C(O)=O)c4[nH]c(cc1n2)c(C)c4C(O)=O)c(C)c3C=C
References
Nishie H, Kataoka H, Yano S, Yamaguchi H, Nomoto A, Tanaka M, Kato A, Shimura T, Mizoshita T, Kubota E, Tanida S, Joh T. Excellent antitumor effects for gastrointestinal cancers using photodynamic therapy with a novel glucose conjugated chlorin e6. Biochem Biophys Res Commun. 2018 Feb 19;496(4):1204-1209. doi: 10.1016/j.bbrc.2018.01.171. Epub 2018 Jan 31. PubMed PMID: 29408755.
Takahashi T, Suzuki S, Misawa S, Akimoto J, Shinoda Y, Fujiwara Y. Photodynamic therapy using talaporfin sodium induces heme oxygenase-1 expression in rat malignant meningioma KMY-J cells. J Toxicol Sci. 2018;43(5):353-358. doi: 10.2131/jts.43.353. PubMed PMID: 29743446.
Shimizu K, Nitta M, Komori T, Maruyama T, Yasuda T, Fujii Y, Masamune K, Kawamata T, Maehara T, Muragaki Y. Intraoperative Photodynamic Diagnosis Using Talaporfin Sodium Simultaneously Applied for Photodynamic Therapy against Malignant Glioma: A Prospective Clinical Study. Front Neurol. 2018 Jan 30;9:24. doi: 10.3389/fneur.2018.00024. eCollection 2018. PubMed PMID: 29441040; PubMed Central PMCID: PMC5797572.
Fuse T, Tagami T, Tane M, Ozeki T. Effective light-triggered contents release from helper lipid-incorporated liposomes co-encapsulating gemcitabine and a water-soluble photosensitizer. Int J Pharm. 2018 Apr 5;540(1-2):50-56. doi: 10.1016/j.ijpharm.2018.01.040. Epub 2018 Feb 2. PubMed PMID: 29410222.