Terephthalamidine

TargetMol
Product Code: TAR-T34807
Supplier: TargetMol
CodeSizePrice
TAR-T34807-5mg5mg£850.00
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Quantity:
TAR-T34807-50mg50mg£1,661.00
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Quantity:
TAR-T34807-100mg100mg£2,079.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Terephthalamidine is a derivative of the phthalanilide compounds. Terephthalamidine belongs to a family of compounds which appear to reversibly bind to the minor groove of the DNA double helix but not intercalate DNA. This agent also has been suggested to form ionic complexes with many biological components in vitro, including nucleic acids, proteins and lipids.
CAS:
15411-54-8
Formula:
C8H10N4
Molecular Weight:
162.196
Purity:
0.98
SMILES:
NC(=N)c1ccc(cc1)C(N)=N

References

Shu Y, Lei H, Tan YN, Meng M, Zhang XC, Liu CY. Tuning the electronic coupling in Mo2-Mo2 systems by variation of the coordinating atoms of the bridging ligands. Dalton Trans. 2014 Oct 21;43(39):14756-65. doi: 10.1039/c4dt00786g. PubMed PMID: 25157859. Abergel RJ, Raymond KN. Multidentate terephthalamidate and hydroxypyridonate ligands: towards new orally active chelators. Hemoglobin. 2011;35(3):276-90. doi: 10.3109/03630269.2011.560771. PubMed PMID: 21599440. Leyden R, Velasco-Torrijos T, Andr? S, Gouin S, Gabius HJ, Murphy PV. Synthesis of bivalent lactosides based on terephthalamide, N,N'-diglucosylterephthalamide, and glycophane scaffolds and assessment of their inhibitory capacity on medically relevant lectins. J Org Chem. 2009 Dec 4;74(23):9010-26. doi: 10.1021/jo901667r. PubMed PMID: 19899775. Procacci P, Ferrari F, Bettini G, Bissolotti G, Trevisiol L, Nocini PF. Soccer-related facial fractures: postoperative management with facial protective shields. J Craniofac Surg. 2009 Jan;20(1):15-20. doi: 10.1097/SCS.0b013e3181909c55. PubMed PMID: 19164981.