Bimolane

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TargetMol
Product Code: TAR-T3481
Supplier: TargetMol
CodeSizePrice
TAR-T3481-2mg2mg£99.00
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TAR-T3481-5mg5mg£112.00
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Quantity:
TAR-T3481-10mg10mg£140.00
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TAR-T3481-25mg25mg£238.00
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Quantity:
TAR-T3481-50mg50mg£360.00
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Quantity:
TAR-T3481-100mg100mg£466.00
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TAR-T3481-500mg500mg£970.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Bimolane is a topoisomerase II inhibitor.
CAS:
74550-97-3
Formula:
C20H32N6O6
Molecular Weight:
452.512
Pathway:
DNA Damage/DNA Repair
Purity:
0.9929
SMILES:
O=C1CN(CCN2CC(=O)N(CN3CCOCC3)C(=O)C2)CC(=O)N1CN1CCOCC1
Target:
Topoisomerase

References

Vuong MC, Hasegawa LS, Eastmond DA. A comparative study of the cytotoxic and genotoxic effects of ICRF-154 and bimolane, two catalytic inhibitors of topoisomerase II. Mutat Res. 2013 Jan 20;750(1-2):63-71. Frantz CE, Smith H, Eades DM, Grosovsky AJ, Eastmond DA. Bimolane: in vitro inhibitor of human topoisomerase II. Cancer Lett. 1997 Dec 9;120(2):135-40. Roy SK, Eastmond DA. Bimolane induces multiple types of chromosomal aberrations in human lymphocytes in vitro. Mutat Res. 2011 Dec 24;726(2):181-7.