Terpentecin
| Code | Size | Price |
|---|
| TAR-T34810-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Terpentecin is isolated from strain MF730-N6 and is active against leukemia L-1210 and Ehrlich ascites carcinoma.
CAS:
100440-25-3
Formula:
C20H28O6
Molecular Weight:
364.438
Purity:
0.98
SMILES:
[H][C@]12CCC=C(C)[C@]1(C)C(=O)[C@@H](O)C(C)C2(C)C[C@H](O)[C@]1(CO1)C(=O)C=O
References
Kawada S, Yamashita Y, Fujii N, Nakano H. Induction of a heat-stable topoisomerase II-DNA cleavable complex by nonintercalative terpenoides, terpentecin and clerocidin. Cancer Res. 1991 Jun 1;51(11):2922-5. PubMed PMID: 1851667.
Dairi T, Motohira Y, Kuzuyama T, Takahashi S, Itoh N, Seto H. Cloning of the gene encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase from terpenoid antibiotic-producing Streptomyces strains. Mol Gen Genet. 2000 Jan;262(6):957-64. PubMed PMID: 10660057.
Isshiki K, Tamamura T, Sawa T, Naganawa H, Takeuchi T, Umezawa H. Biosynthetic studies of terpentecin. J Antibiot (Tokyo). 1986 Nov;39(11):1634-5. PubMed PMID: 3793635.
Tamamura T, Tsuchiya M, Isshiki K, Sawa T, Takeuchi T, Hori M, Sakata N. Terpentecin, an inhibitor of DNA synthesis. J Antibiot (Tokyo). 1988 May;41(5):648-54. PubMed PMID: 3290173.