TargetMol

Terpentecin

Product Code:
 
TAR-T34810
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T34810-5mg5mg£850.00
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Further Information

Bioactivity:
Terpentecin is isolated from strain MF730-N6 and is active against leukemia L-1210 and Ehrlich ascites carcinoma.
CAS:
100440-25-3
Formula:
C20H28O6
Molecular Weight:
364.438
Purity:
0.98
SMILES:
[H][C@]12CCC=C(C)[C@]1(C)C(=O)[C@@H](O)C(C)C2(C)C[C@H](O)[C@]1(CO1)C(=O)C=O

References

Kawada S, Yamashita Y, Fujii N, Nakano H. Induction of a heat-stable topoisomerase II-DNA cleavable complex by nonintercalative terpenoides, terpentecin and clerocidin. Cancer Res. 1991 Jun 1;51(11):2922-5. PubMed PMID: 1851667. Dairi T, Motohira Y, Kuzuyama T, Takahashi S, Itoh N, Seto H. Cloning of the gene encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase from terpenoid antibiotic-producing Streptomyces strains. Mol Gen Genet. 2000 Jan;262(6):957-64. PubMed PMID: 10660057. Isshiki K, Tamamura T, Sawa T, Naganawa H, Takeuchi T, Umezawa H. Biosynthetic studies of terpentecin. J Antibiot (Tokyo). 1986 Nov;39(11):1634-5. PubMed PMID: 3793635. Tamamura T, Tsuchiya M, Isshiki K, Sawa T, Takeuchi T, Hori M, Sakata N. Terpentecin, an inhibitor of DNA synthesis. J Antibiot (Tokyo). 1988 May;41(5):648-54. PubMed PMID: 3290173.