TargetMol

Tetrahydromethotrexate

Product Code:
 
TAR-T34822
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T34822-5mg5mg£850.00
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Further Information

Bioactivity:
Tetrahydromethotrexate is a folic acid derivative.
CAS:
4299-28-9
Formula:
C20H26N8O5
Molecular Weight:
458.479
Purity:
0.98
SMILES:
CN(CC1CNc2nc(N)nc(N)c2N1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O

References

B?hring U, Shin YS, F?lsch E. The influence of folate antagonists on the metabolism of folic acid and its reduced derivatives in rat liver and kidney. Cancer Res. 1977 Jan;37(1):299-304. PubMed PMID: 830415. Blair JA, Saunders KJ. Preparation of analogs of dl-tetrahydromethotrexate (4-amino-4-deoxy-N10-methyl-dl-5,6,7,8-tetrahydropteroyl-L-monoglutamic acid). Anal Biochem. 1971 Jun;41(2):482-6. PubMed PMID: 5092165. Makulu DR, F?lsch E. Reduced forms of aminopterin and methotrexate in L1210 lymphoma. J Natl Cancer Inst. 1977 Jul;59(1):245-9. PubMed PMID: 875056. Slav?k K, Rode W, Slav?kov? V. Purification of thymidylate synthetase from enzyme-poor sources by affinity chromatography. Biochemistry. 1976 Sep 21;15(19):4222-7. PubMed PMID: 786369.