Thialysine HCl

TargetMol
Product Code: TAR-T34844
Supplier: TargetMol
CodeSizePrice
TAR-T34844-5mg5mg£850.00
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Quantity:
TAR-T34844-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T34844-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Thialysine HCl can be used in protein synthesis and incorporated into proteins in place of lysine.
CAS:
4099-35-8
Formula:
C5H13ClN2O2S
Molecular Weight:
200.68
Purity:
0.98
SMILES:
Cl.NCCSC[C@H](N)C(O)=O

References

Nagar M, Kumar H, Bearne SL. A platform for chemical modification of mandelate racemase: characterization of the C92S/C264S and ?-thialysine 166 variants. Protein Eng Des Sel. 2018 May 30. doi: 10.1093/protein/gzy011. [Epub ahead of print] PubMed PMID: 29850884. Mathieu C, Mac?do JP, H?rlimann D, Wirdnam C, Haindrich AC, Suter Grotemeyer M, Gonz?lez-Salgado A, Schmidt RS, Inbar E, M?ser P, B?tikofer P, Zilberstein D, Rentsch D. Arginine and Lysine Transporters Are Essential for Trypanosoma brucei. PLoS One. 2017 Jan 3;12(1):e0168775. doi: 10.1371/journal.pone.0168775. eCollection 2017. PubMed PMID: 28045943; PubMed Central PMCID: PMC5207785. Daskalova SM, Bhattacharya C, Dedkova LM, Hecht SM. Probing the Flexibility of the Catalytic Nucleophile in the Lyase Catalytic Pocket of Human DNA Polymerase ? with Unnatural Lysine Analogues. Biochemistry. 2017 Jan 24;56(3):500-513. doi: 10.1021/acs.biochem.6b00807. Epub 2017 Jan 12. PubMed PMID: 28005340. Shimizu S, Futase A, Yokoyama T, Ueda S, Honda H. Reduction of FR900525 using an S-(2-aminoethyl) l-cysteine-resistant mutant. J Biosci Bioeng. 2017 Jun;123(6):685-691. doi: 10.1016/j.jbiosc.2017.01.006. Epub 2017 Feb 6. PubMed PMID: 28185832.