Tiliacorine
| Code | Size | Price |
|---|
| TAR-T34879-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Tiliacorine is a dibenzodioxin biphenylalkaloid.
CAS:
27073-72-9
Formula:
C36H38N2O5
Molecular Weight:
578.709
Purity:
0.98
SMILES:
COc1ccc2Cc1c1Cc(C[C@H]3N(C)CCc4cc5Oc6c(OC)cc7CCN(C)[C@@H](C2)c7c6Oc5cc34)ccc1O
References
Dwuma-Badu D, Ayim JS, Fiagbe NY, Tackie AN, Knapp JE, Slatkin DJ, Schiff PL Jr. DIOXINS/*ISOLof West African medicinal plants. XV. Dinklacorine, a new biphenyl dibenzodioxin alkaloid from Tiliacora dinklagei. Lloydia. 1976 Jul-Aug;39(4):213-7. PubMed PMID: 957910.
Sureram S, Senadeera SP, Hongmanee P, Mahidol C, Ruchirawat S, Kittakoop P. Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2902-5. doi: 10.1016/j.bmcl.2012.02.053. Epub 2012 Feb 23. PubMed PMID: 22418278.
Seal T, Mukherjee B. (+)-Tiliarine, a selective in vitro inhibitor of human melanoma cells. Phytother Res. 2002 Sep;16(6):596-9. PubMed PMID: 12237824.
Nayak T, Jena L, Waghmare P, Harinath BC. Identification of potential inhibitors for mycobacterial uridine diphosphogalactofuranose-galactopyranose mutase enzyme: A novel drug target through in silico approach. Int J Mycobacteriol. 2018 Jan-Mar;7(1):61-68. doi: 10.4103/ijmy.ijmy_174_17. PubMed PMID: 29516888.