1400W dihydrochloride

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TargetMol
Product Code: TAR-T3491
Supplier: TargetMol
CodeSizePrice
TAR-T3491-5mg5mg£105.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3491-1mL1 mL * 10 mM (in DMSO)£109.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3491-10mg10mg£125.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3491-25mg25mg£173.00
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Quantity:
TAR-T3491-50mg50mg£256.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3491-100mg100mg£386.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3491-200mg200mg£481.00
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Quantity:
TAR-T3491-500mg500mg£736.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
1400 W is a highly effective and specific inhibitor of inducible NOS2 (iNOS).
CAS:
214358-33-5
Formula:
C10H17Cl2N3
Molecular Weight:
250.17
Pathway:
Immunology/Inflammation
Purity:
0.9947
SMILES:
Cl.Cl.CC(=N)NCc1cccc(CN)c1
Target:
NOS; NO Synthase

References

Thomsen LL, et al. Cancer Res. 1997, 57(15):3300-4. Cai J, Zhang X, Chen P, et al. The ER stress sensor inositol-requiring enzyme 1? in Kupffer cells promotes hepatic ischemia-reperfusion injury. Journal of Biological Chemistry. 2021: 101532. Garvey EP, et al. J Biol Chem. 199, 272(8):4959-63. Ersoz N, et al. Ren Fail. 2009, 31(8):704-10. Sen N, et al. Nat Cell Biol. 2008, 10(7):866-73.