Vinthionine
| Code | Size | Price |
|---|
| TAR-T35061-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T35061-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T35061-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Vinthionine binds covalently to rat liver DNA, RNA, and protein in vivo, but not in vitro.
CAS:
70858-14-9
Formula:
C6H11NO2S
Molecular Weight:
161.22
Purity:
0.98
SMILES:
N[C@@H](CCSC=C)C(O)=O
References
Catcott KC, Yan J, Qu W, Wysocki VH, Zhou ZS. Identifying Unknown Enzyme-Substrate Pairs from the Cellular Milieu with Native Mass Spectrometry. Chembiochem. 2017 Apr 4;18(7):613-617. doi: 10.1002/cbic.201600634. Epub 2017 Mar 14. PubMed PMID: 28140508.
Sohn YW, Lee GH, Liem A, Miller JA. Activation of H-ras oncogenes in male B6C3F1 mouse liver tumors induced by vinthionine or 2-chloroethyl-methyl sulfide. Carcinogenesis. 1996 Jun;17(6):1361-4. PubMed PMID: 8681456.
Vaughan MD, Su Z, Daub E, Honek JF. Intriguing cellular processing of a fluorinated amino acid during protein biosynthesis in Escherichia coli. Org Biomol Chem. 2016 Sep 26;14(38):8942-8946. PubMed PMID: 27722405.
Qu W, Catcott KC, Zhang K, Liu S, Guo JJ, Ma J, Pablo M, Glick J, Xiu Y, Kenton N, Ma X, Duclos RI Jr, Zhou ZS. Capturing Unknown Substrates via in Situ Formation of Tightly Bound Bisubstrate Adducts: S-Adenosyl-vinthionine as a Functional Probe for AdoMet-Dependent Methyltransferases. J Am Chem Soc. 2016 Mar 9;138(9):2877-80. doi: 10.1021/jacs.5b05950. Epub 2016 Feb 29. PubMed PMID: 26901520.