STO-609
Code | Size | Price |
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TAR-T3546-1mg | 1mg | £121.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3546-1mL | 1 mL * 10 mM (in DMSO) | £187.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3546-5mg | 5mg | £187.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3546-10mg | 10mg | £270.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3546-25mg | 25mg | £434.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3546-50mg | 50mg | £606.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3546-100mg | 100mg | £833.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3546-500mg | 500mg | £1,589.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
STO-609 is a specific and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK) for recombinant CaM-KKα/KKβ (Ki: 80/15 ng/mL).
CAS:
52029-86-4
Formula:
C19H10N2O3
Molecular Weight:
314.3
Pathway:
Chromatin/Epigenetic; Neuroscience; Autophagy; PI3K/Akt/mTOR signaling
Purity:
0.9895
SMILES:
OC(=O)c1ccc2c3nc4ccccc4n3c(=O)c3cccc1c23
Target:
CaMK; AMPK; Autophagy
References
Xu J, Xu X, Ling Y, et al.Vincamine as an agonist of G-protein-coupled receptor 40 effectively ameliorates diabetic peripheral neuropathy in mice.Acta Pharmacologica Sinica.2023: 1-16.
Kukimoto-Niino M,et al. Crystal structure of the Ca??/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609. J Biol Chem. 2011 Jun 24;286(25):22570-9.
Tokumitsu H,rt al. STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase. J Biol Chem. 2002 May 3;277(18):15813-8. Epub 2002 Feb 26.
Kan J, Zhao C, Lu S, et al. S100A16, a novel lipogenesis promoting factor in livers of mice and hepatocytes in vitro[J]. Journal of cellular physiology. 2019 May 8.
Kan J, Zhao C, Lu S, et al. S100A16, a novel lipogenesis promoting factor in livers of mice and hepatocytes in vitro. Journal of Cellular Physiology. 2019 May 8