Graphislactone A
| Code | Size | Price |
|---|
| TAR-T35590-5mg | 5mg | £1,462.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislactone A reduces peroxidation of human LDL and slows peroxidation of linoleic acid by 4.4-fold. It also inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM.
CAS:
52179-44-9
Formula:
C16H14O6
Molecular Weight:
302.282
Purity:
0.98
SMILES:
COc1cc(O)c2c(c1)c1c(C)cc(OC)c(O)c1oc2=O
References
Hormazabal, E., Schmeda-Hirschmann, G., Astudillo, L., et al. Metabolites from Microsphaeropsis olivacea, an endophytic fungus of Pilgerodendron uviferum Z. Naturforsch. C. 60(1-2), 11-21 (2005).
Song, Y.C., Huang, W.Y., Sun, C., et al. Characterization of graphislactone A as the antioxidant and free radical-scavenging substance from the culture of Cephalosporium sp. IFB-E001, an endophytic fungus in Trachelospermum jasminoides Biol. Pharm. Bull. 28(3), 506-509 (2005).