Lithocholic Acid 3-sulfate (sodium salt)
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| TAR-T35797-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T35797-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lithocholic acid 3-sulfate is a metabolite of the secondary bile acid lithocholic acid.[1] It is water soluble and the primary form of lithocholic acid in the bile duct. Lithocholic acid 3-sulfate forms a complex with calcium in vitro.[2] Biliary secretion of lithocholic acid 3-sulfate is increased in a rat model of diabetes induced by streptozotocin.[3]
CAS:
64936-81-8
Formula:
C24H40Na2O7S
Molecular Weight:
518.62
Purity:
0.98
SMILES:
O.[Na+].[Na+].CC(CCC([O-])=O)C1CCC2C3CCC4CC(CCC4(C)C3CCC12C)OS([O-])(=O)=O
References
Kirkpatrick, R.B., and Kraft, B.G. Effect of streptozotocin-induced diabetes on bile acid sulfation in male rat liver. Am. J. Physiol. 247(3 Pt 1), G226-G230 (1984).
Borriello, S.P., and Owen, R.W. The metabolism of lithocholic acid and lithocholic acid-3-?-sulfate by human fecal bacteria. Lipids 17(7), 477-482 (1982).
Oelberg, D.G., Dubinsky, W.P., Adcock, E.W., et al. Calcium binding by lithocholic acid derivatives. Am. J. Physiol. 247(1 Pt 1), G112-G115 (1984).