FIPI HCl
Code | Size | Price |
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TAR-T3580L-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3580L-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3580L-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
FIPI is an effective and selective phospholipase D inhibitor that reduces mercury-induced lipid signaling and thus protects aortic endothelial cells from cytotoxicity.
CAS:
1781834-93-2
Formula:
C23H25ClFN5O2
Molecular Weight:
457.93
Purity:
0.98
SMILES:
Cl.Fc1ccc2[nH]c(cc2c1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
References
Akekawatchai C, Roytrakul S, Kittisenachai S, Isarankura-Na-Ayudhya P, Jitrapakdee S. Protein Profiles Associated with Anoikis Resistance of Metastatic MDA-MB-231 Breast Cancer Cells. Asian Pac J Cancer Prev. 2016;17(2):581-90. PubMed PMID: 26925647.
Bj?rnstr?m K, Turina D, Strid T, Sundqvist T, Eintrei C. Orexin A inhibits propofol-induced neurite retraction by a phospholipase D/protein kinase C?-dependent mechanism in neurons. PLoS One. 2014 May 14;9(5):e97129. doi: 10.1371/journal.pone.0097129. eCollection 2014. PubMed PMID: 24828410; PubMed Central PMCID: PMC4020800.
McDavid S, Bauer MB, Brindley RL, Jewell ML, Currie KP. Butanol isomers exert distinct effects on voltage-gated calcium channel currents and thus catecholamine secretion in adrenal chromaffin cells. PLoS One. 2014 Oct 2;9(10):e109203. doi: 10.1371/journal.pone.0109203. eCollection 2014. PubMed PMID: 25275439; PubMed Central PMCID: PMC4183593.
Ganesan R, Mahankali M, Alter G, Gomez-Cambronero J. Two sites of action for PLD2 inhibitors: The enzyme catalytic center and an allosteric, phosphoinositide biding pocket. Biochim Biophys Acta. 2015 Mar;1851(3):261-72. doi: 10.1016/j.bbalip.2014.12.007. Epub 2014 Dec 20. PubMed PMID: 25532944; PubMed Central PMCID: PMC4312721.