Linearmycin A
| Code | Size | Price |
|---|
| TAR-T36048-5mg | 5mg | £1,764.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Linearmycin A is a polyene antibiotic that has been found inStreptomyces.1It is active against the bacteriaS. aureusandE. coli(MICs = 3.1 and 1.6 μg/disc, respectively), the fungiS. cerevisiaeandC. albicans(MICs = 0.1 and 1.6 μg/disc, respectively), and the plant pathogenic fungusA. nigerin disc assays (MIC = 0.2 μg/disc). Linearmycin A induces lysis and degradation ofB. subtilisas a component ofStreptomycesMg1 extract.2
CAS:
163596-98-3
Formula:
C64H101NO16
Molecular Weight:
1140.5
Purity:
0.98
SMILES:
NCCC[C@@H](O)C[C@@H](O)C/C=C/C(O)C/C=C/[C@@H](O)C[C@H](O)C[C@@H](O)C[C@H](O)C/C=C/[C@H](C[C@@H](O)CC(CC(C(C(C/C=C/C=C/C=C/C=C/C=C/[C@@H](O)[C@H](C)[C@@H](O)C(C)/C=C/CC/C=C/C=C/C=C/C=C(C)/C(O)=O)O)C)=O)O)O
References
Stubbendieck, R.M., and Straight, P.D.Escape from lethal bacterial competition through coupled activation of antibiotic resistance and a mobilized subpopulationPLoS Genet.11(12)e1005722(2015)
Sakuda, S., Guce-Bigol, U., Itoh, M., et al.Novel linear polyene antibiotics: LinearmycinsJ. Chem. Soc., Perkin Trans. 1182315-2319(1996)