Quinaldopeptin
| Code | Size | Price |
|---|
| TAR-T36181-5mg | 5mg | £3,178.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 μg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 μg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).
CAS:
130743-07-6
Formula:
C62H78N14O14
Molecular Weight:
1243.4
Purity:
0.98
SMILES:
O=C(CN(C)C(CNC([C@@]1([H])N(C([C@@](NC(C2=NC(C=CC=C3)=C3C=C2O)=O)([H])[C@H](C)NC([C@@]4([H])N5CCCC4)=O)=O)CCCC1)=O)=O)N(CCCC6)[C@]6([H])C(N[C@@H](C)[C@](NC(C7=NC(C=CC=C8)=C8C=C7O)=O)([H])C(N9CCCC[C@@]9([H])C(NCC(N(C)CC5=O)=O)=O)=O)=O