NR 7h

TargetMol
Product Code: TAR-T36260
Supplier: TargetMol
CodeSizePrice
TAR-T36260-5mg5mg£518.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Further Information

Bioactivity:
Potent and selective p38α and p38β degrader (DC50 < 50 nM). Displays no significant degradation of p38γ, p38δ, JNK1/2 or ERK1/2. Inhibits phosphorylation of MK2 in UV-treated cancer cells and LPS-stimulated bone marrow-derived macrophages (BMDM). Exhibits similar effect to p38α gene knockout in BBL358 cells. Active in vivo.
CAS:
0
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0