12-hydroxy Stearic Acid
| Code | Size | Price |
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| TAR-T36456-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T36456-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
12-hydroxy Stearic acid is a hydroxy fatty acid produced by the hydrogenation of ricinoleic acid .1It is a low molecular weight gelator that self-assembles to form organogels.2Administration of paclitaxel in 12-hydroxy stearic acid-containing gel nanocarriers enhances tumor growth suppression in an H22 murine hepatocellular carcinoma model.3Formulations containing 12-hydroxy stearic acid have been used in cosmetic products as emollients.
CAS:
106-14-9
Formula:
C18H36O3
Molecular Weight:
300.483
Purity:
0.98
SMILES:
CCCCCCC(O)CCCCCCCCCCC(O)=O
References
Burkhardt, M., Noirez, L., and Gradzielski, M.Organogels based on 12-hydroxy stearic acid as a leitmotif: Dependence of gelation properties on chemical modificationsJ. Colloid Interface Sci.466369-376(2016)
He, W., Lv, Y., Zhao, Y., et al.Core-shell structured gel-nanocarriers for sustained drug release and enhanced antitumor effectInt. J. Pharm.484(1-2)163-171(2015)
Fameau, A.-L., and Rogers, M.A.The curious case of 12-hydroxystearic acid ? the Dr. Jekyll & Mr. Hyde of molecular gelatorsCurr. Opin. Colloid Interface Sci.4568-82(2020)