CAY10730

TargetMol
Product Code: TAR-T36459
Supplier: TargetMol
CodeSizePrice
TAR-T36459-5mg5mg£192.00
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TAR-T36459-10mg10mg£291.00
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TAR-T36459-25mg25mg£565.00
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TAR-T36459-50mg50mg£876.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
CAY10730 is a turn-on fluorescent probe for the detection of nitroreductase activity, a marker of hypoxia. In the presence of nitroreductase, CAY10730 is transformed into a highly fluorescent molecule that displays excitation/emission maxima of 454/520 nm, respectively. It is selective for nitroreductase over a variety of bioanalytes, including glutathione, ascorbic acid, and reactive oxygen species such as H2O2. CAY10730 (1 μM) has been used to detect hypoxia in A549 human lung carcinoma cells.
CAS:
2206677-06-5
Formula:
C28H19NO7
Molecular Weight:
481.5
Purity:
0.98
SMILES:
COC(C=C1)=CC2=C1C3(C(C=CC=C4)=C4C(O3)=O)C(C=CC(OCC5=CC=C([N+]([O-])=O)C=C5)=C6)=C6O2