PTIO

TargetMol
Product Code: TAR-T36512
Supplier: TargetMol
CodeSizePrice
TAR-T36512-5mg5mg£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T36512-1mL1 mL * 10 mM (in DMSO)£117.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
PTIO is a specific scavenger of NO. PTIO reacts with nitric oxide to form nitric dioxide and corresponding imino nitroxides. PTIO can be used to examine nitric oxide synthase inhibitory activity.
CAS:
18390-00-6
Formula:
C13H17N2O2
Molecular Weight:
233.291
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
CC1(C)N([O])C(c2ccccc2)=[N+]([O-])C1(C)C
Target:
NO Synthase

References

Goldstein S, et al. Reactions of PTIO and carboxy-PTIO with *NO, *NO2, and O2-*. J Biol Chem. 2003;278(51):50949-50955. Xia JL , et al. Putrescine regulates nitric oxide accumulation in Ganoderma lucidum partly by influencing cellular glutamine levels under heat stress. Microbiol Res. 2020;239:126521.