TargetMol

Hydroxysafflor yellow A

Product Code:
 
TAR-T3674
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3674-1mL1 mL * 10 mM (in DMSO)£119.00
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Quantity:
TAR-T3674-20mg20mg£127.00
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Further Information

Bioactivity:
Hydroxysafflor yellow A inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacity and inhibiting the expression of TGF-β. It prevents steroid-induced avascular necrosis of femoral head by inhibiting primary bone marrow-derived mesenchymal stromal cells. Also, Hydroxysafflor yellow A has anti-tumor effects.
CAS:
78281-02-4
Formula:
C27H32O16
Molecular Weight:
612.537
Pathway:
Stem Cells
Purity:
0.9999
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)C1=C(O)C(O)([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C(O)=C(C(=O)C=Cc2ccc(O)cc2)C1=O
Target:
TGF-beta/Smad

References

Miao T, Qian L, Yu F, et al. Protective effects of hydroxysafflor yellow an on high oxidized low density lipoprotein induced human coronary artery endothelial cells injuries. development. 2019, 22: 581-589. Zhu HJ, et al. Cytotechnology. 2015 Oct;67(5):885-92. Miao T, Qian L, Yu F, et al. Protective effects of hydroxysafflor yellow an on high oxidized low density lipoprotein induced human coronary artery endothelial cells injuries. Development. 2019, 22: 581-589 Liu YL, et al. Int Immunopharmacol. 2014 Dec;23(2):649-57. He Y, et al. J Physiol Biochem. 2015 Mar;71(1):69-78. Jin M, et al. Hydroxysafflor yellow A attenuate lipopolysaccharide-induced endothelium inflammatory injury. Chin J Integr Med. 2015 May 27. Yang F, et al. Eur J Pharmacol. 2015 May 5;754:105-14.