1-Alaninechlamydocin
| Code | Size | Price |
|---|
| TAR-T36797-5mg | 5mg | £1,866.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
1-Alaninechalmydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs). It reduces total HDAC activity in HeLa cell lysates in a concentration-dependent manner. 1-Alaninechlamydocin reduces proliferation of MIA PaCa-2, PANC-1, and hTERT-HPNE cells (GI50s = 5.3, 14, and 2.0 nM, respectively).
CAS:
141446-96-0
Formula:
C27H36N4O6
Molecular Weight:
512.6
Purity:
0.98
SMILES:
O=C(N[C@@H](CCCCCC([C@@H]1CO1)=O)C(N[C@H]2C)=O)[C@]3([H])N(CCC3)C([C@H](CC4=CC=CC=C4)NC2=O)=O