Quinacrine mustard (hydrochloride)
Code | Size | Price |
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TAR-T37031-5mg | 5mg | £189.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T37031-10mg | 10mg | £278.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T37031-25mg | 25mg | £535.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T37031-50mg | 50mg | £929.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Quinacrine mustard is a fluorescent DNA-intercalating agent.1 It selectively binds to adenine-thymine (AT) base pairs over guanine-cytosine (GC) base pairs.2,3 Quinacrine mustard has been used to label metaphase chromosomes for karyotyping by autoradiography.1 It displays excitation/emission maxima of 425/480 nm, respectively.4
CAS:
4213-45-0
Formula:
C23H28Cl3N3O ? 2HCl
Molecular Weight:
541.8
Pathway:
Autophagy
Purity:
0.98
SMILES:
COC1=CC2=C(C=C1)N=C3C(C=CC(Cl)=C3)=C2NC(CCCN(CCCl)CCCl)C.Cl.Cl
Target:
Autophagy
References
Caspersson T, et al. Fluorescent labeling of chromosomal DNA: superiority of quinacrine mustard to quinacrine. Science. 1970;170(3959):762.
Chen RF. Fluorescence of quinacrine mustard conjugated to proteins. Arch Biochem Biophys. 1976;172(1):39-50.
Kapuscinski J, et al. The modulation of the DNA-damaging effect of polycyclic aromatic agents by xanthines. Part I. Reduction of cytostatic effects of quinacrine mustard by caffeine. Biochem Pharmacol. 2002;63(4):625-634.
Piosik J, et al. Alleviation of mutagenic effects of polycyclic aromatic agents (quinacrine mustard, ICR-191 and ICR-170) by caffeine and pentoxifylline. Mutat Res. 2003;530(1-2):47-57.