TargetMol

Quinacrine mustard (hydrochloride)

Product Code:
 
TAR-T37031
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37031-5mg5mg£189.00
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TAR-T37031-10mg10mg£278.00
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TAR-T37031-25mg25mg£535.00
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TAR-T37031-50mg50mg£929.00
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This product comes from: United States.
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Further Information

Bioactivity:
Quinacrine mustard is a fluorescent DNA-intercalating agent.1 It selectively binds to adenine-thymine (AT) base pairs over guanine-cytosine (GC) base pairs.2,3 Quinacrine mustard has been used to label metaphase chromosomes for karyotyping by autoradiography.1 It displays excitation/emission maxima of 425/480 nm, respectively.4
CAS:
4213-45-0
Formula:
C23H28Cl3N3O ? 2HCl
Molecular Weight:
541.8
Pathway:
Autophagy
Purity:
0.98
SMILES:
COC1=CC2=C(C=C1)N=C3C(C=CC(Cl)=C3)=C2NC(CCCN(CCCl)CCCl)C.Cl.Cl
Target:
Autophagy

References

Caspersson T, et al. Fluorescent labeling of chromosomal DNA: superiority of quinacrine mustard to quinacrine. Science. 1970;170(3959):762. Chen RF. Fluorescence of quinacrine mustard conjugated to proteins. Arch Biochem Biophys. 1976;172(1):39-50. Kapuscinski J, et al. The modulation of the DNA-damaging effect of polycyclic aromatic agents by xanthines. Part I. Reduction of cytostatic effects of quinacrine mustard by caffeine. Biochem Pharmacol. 2002;63(4):625-634. Piosik J, et al. Alleviation of mutagenic effects of polycyclic aromatic agents (quinacrine mustard, ICR-191 and ICR-170) by caffeine and pentoxifylline. Mutat Res. 2003;530(1-2):47-57.