L-asarinin
| Code | Size | Price |
|---|
| TAR-T3765-1mL | 1 mL * 10 mM (in DMSO) | £135.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T3765-20mg | 20mg | £183.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Asarinin reduces peripheral blood concentration of IL-12 and inhibits the expression of CXCR3 and TLR4, which means Asarinin may have a role on the TLR4 pathway and produce prolongation of allograft heart survival.
CAS:
133-05-1
Formula:
C20H18O6
Molecular Weight:
354.36
Purity:
0.98
SMILES:
C5O[C@@H](c1ccc2OCOc2c1)[C@H]6CO[C@H](c3ccc4OCOc4c3)[C@@H]56
References
Bogurcu N., et al. ALCAPs induce mitochondrial apoptosis and activate DNA damage response by generating ROS and inhibiting topoisomerase I enzyme activity in K562 leukemia cell line. Biochem Biophys Res Commun. 2011 Jun 17;409(4):738-44.
Gu J., et al. The effect of Asarinin on Toll-like pathway in rats after cardiac allograft implantation. Transplant Proc. 2015 Mar;47(2):545-8.