Armepavine
| Code | Size | Price |
|---|
| TAR-T3775-5mg | 5mg | £295.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Armepavine exerted both in vitro and in vivo antifibrotic effects in rats, with inhibition of NF-κB, JunD and C/EBP pathways. It improves experimental autoimmune crescentic glomerulonephritis.
CAS:
524-20-9
Formula:
C19H23NO3
Molecular Weight:
313.397
Pathway:
NF-κb
Purity:
0.95
SMILES:
COc1cc2CCN(C)[C@H](Cc3ccc(O)cc3)c2cc1OC
Target:
IκB/IKK; NF-κB
References
Ka SM, et al. (S)-armepavine from Chinese medicine improves experimental autoimmune crescentic glomerulonephritis. Rheumatology (Oxford). 2010 Oct;49(10):1840-51.
Weng TC, et al. Effects of armepavine against hepatic fibrosis induced by thioacetamide in rats. Phytother Res. 2012 Mar;26(3):344-53.