Oroxin B
| Code | Size | Price |
|---|
| TAR-T3780-1mL | 1 mL * 10 mM (in DMSO) | £143.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T3780-20mg | 20mg | £159.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Oroxin B has antioxidant activity.
CAS:
114482-86-9
Formula:
C27H30O15
Molecular Weight:
594.522
Pathway:
oxidation-reduction; PI3K/Akt/mTOR signaling; Apoptosis; Autophagy
Purity:
0.9822
SMILES:
OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc4oc(cc(=O)c4c(O)c3O)-c3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Target:
Apoptosis; PTEN; Antioxidant; PI3K; Autophagy
References
Huang R, Li S, Tian C, et al. Thermal stress involved in TRPV2 promotes tumorigenesis through the pathway of PI3K/Akt/mTOR in esophageal squamous cell carcinoma. british journal of cancer. 2022 Nov;127(8):1424-1439.
Qiu J1,et al. Molecular modeling reveals the novel inhibition mechanism and binding mode of three natural compounds to staphylococcal ?-hemolysin.PLoS One. 2013 Nov 27;8(11):e820197.
Huang R, Li S, Tian C, et al. Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma. British Journal of Cancer. 2022: 1-16.
Huang R, Li S, Tian C, et al. Thermal stress involved in TRPV2 promotes tumorigenesis through the pathway of PI3K/Akt/mTOR in esophageal squamous cell carcinoma[J].
Li DQ,et al. Discovery of xanthine oxidase inhibitors from a complex mixture using an online, restricted-access material coupled with column-switching liquid chromatography with a diode-array detection system. Anal Bioanal Chem. 2014 Mar;406(7):1975-84.
Huang J, Wang C, Lu S, et al. Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity. Drug Design, Development and Therapy. 2021, 15: 4811-4825.