Didymin
| Code | Size | Price |
|---|
| TAR-T3787-5mg | 5mg | £124.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T3787-10mg | 10mg | £164.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Didymin has antioxidant property. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma, may used for neuroblastoma therapy. Didymin may be a potential therapeutic molecule for the treatment of neurodegenerative disorders associated with oxidative stress.
CAS:
14259-47-3
Formula:
C28H34O14
Molecular Weight:
594.566
Pathway:
; Apoptosis
Purity:
0.9987
SMILES:
COc1ccc(cc1)[C@@H]1CC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2O1
Target:
Apoptosis;
References
Xiao Y Z, Yang M, Xiao Y, et al. Reducing Hypothalamic Stem Cell Senescence Protects against Aging-Associated Physiological Decline[J]. Cell Metabolism. 2020
Morelli S, et al. Neuroprotective effect of didymin on hydrogen peroxide-induced injury in the neuronal membrane system. Cells Tissues Organs. 2014;199(2-3):184-200.
Xiao Y Z, Yang M, Xiao Y, et al. Reducing Hypothalamic Stem Cell Senescence Protects against Aging-Associated Physiological Decline. Cell Metabolism. 2020-31(3) 534-548