TargetMol

Icariside I

Product Code:
 
TAR-T3808
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3808-1mL1 mL * 10 mM (in DMSO)£124.00
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Quantity:
TAR-T3808-20mg20mg£167.00
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Further Information

Bioactivity:
Icariin is isolated from Epimedium herb. It can stimulate osteogenic differentiation of BMSCs and inhibit bone resorption activity of osteoclasts.
CAS:
56725-99-6
Formula:
C27H30O11
Molecular Weight:
530.526
Purity:
0.9947
SMILES:
COc1ccc(cc1)-c1oc2c(CC=C(C)C)c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc(O)c2c(=O)c1O

References

Ming LG,et al. Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling. J Cell Physiol. 2013 Mar;228(3):513-21 Gao Y, Xu G, Ma L, et al. Icarisid I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity. Cell Communication and Signaling. 2020 Gao Y, Xu G, Ma L, et al. Icarisid I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2020 Gao Y, Xu G, Ma L, et al. Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity. Cell Communication and Signaling. 2021 Feb 11;19(1):13. doi: 10.1186/s12964-020-00647-1. Gao Y, Xu G, Ma L, et al. Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2021, 19(1): 1-14. Hou M, Li H, He T, et al.Icariside I reduces breast cancer proliferation, apoptosis, invasion, and metastasis probably through inhibiting IL-6/STAT3 signaling pathway.Journal of Pharmacy and Pharmacology.2023: rgad103.