GYKI-47261 dihydrochloride
| Code | Size | Price |
|---|
| TAR-T38601-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
GYKI-47261 dihydrochloride is a competitive, orally active, and selective AMPA receptor antagonist with an IC 50 of 2.5 μM. GYKI-47261 has broad spectrum anticonvulsive activity and neuroprotective effects. GYKI-47261 dihydrochloride is also a potent inducer of CYP2E1.
CAS:
1217049-32-5
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Abrah?m G, et al. New non competitive AMPA antagonists. Bioorg Med Chem. 2000;8(8):2127-2143.
Tam?si V, et al. GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl)propionic acid] antagonist, is a CYP2E1 inducer. Drug Metab Dispos. 2003;31(11):1310-1314.