Mant-GTPγS

TargetMol
Product Code: TAR-T38782
Supplier: TargetMol
CodeSizePrice
TAR-T38782-5mg5mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Mant-GTPγS, a GTP mimetic, is a potent competitive adenylyl cyclase (AC) inhibitor. Mant-GTPγS is a potent YdeH inhibitor.
CAS:
136749-24-1
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Andreas Gille, et al. 2'(3')-O-(N-methylanthraniloyl)-substituted GTP analogs: a novel class of potent competitive adenylyl cyclase inhibitors. J Biol Chem. 2003 Apr 11;278(15):12672-9. Christian Spangler, et al. Interaction of the diguanylate cyclase YdeH of Escherichia coli with 2',(3')-substituted purine and pyrimidine nucleotides. J Pharmacol Exp Ther. 2011 Jan;336(1):234-41. Tomoharu Kanie, et al. The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Dev Cell. 2017 Jul 10;42(1):22-36.e12.