TargetMol

SBP-0636457

Product Code:
 
TAR-T38857
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38857-5mg5mg£870.00
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Further Information

Bioactivity:
SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins , with a K i of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers.
CAS:
1422180-49-1
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Finlay D, et, al. Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins. F1000Res. 2017 Apr 27; 6:587. Finlay D, et, al. Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs. Mol Cancer Ther. 2014 Jan; 13(1): 5-15.