SR-1277
| Code | Size | Price |
|---|
| TAR-T38927-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SR-1277 is a potent, selective and ATP competitive CK1δ/ε inhibitor, with IC 50 s of 49 nM and 260 nM, respectively. SR-1277 also inhibits FLT3 , CDK4/cyclin D1 , CDK6/cyclin D3 and CDK9/cyclin K , with IC 50 s of 305 nM, 1340 nM, 311 nM and 109 nM, respectively. SR-1277 can be used for the research of cancer.
CAS:
1446715-47-4
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Bibian M, et, al. Development of highly selective casein kinase 1?/1? (CK1?/?) inhibitors with potent antiproliferative properties. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4374-80.