BMSpep-57
| Code | Size | Price |
|---|
| TAR-T39106-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC 50 of 7.68 nM. BMSpep-57 binds to PD-L1 with K d s of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 facilitates T cell function by in creasing IL-2 production in PBMCs.
CAS:
1629655-80-6
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Aravindhan Ganesan, et al. Comprehensive in vitro characterization of PD-L1 small molecule inhibitors.Sci Rep . 2019 Aug 27;9(1):12392.