β-catenin-IN-37
Code | Size | Price |
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TAR-T39200-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
β-catenin-IN-37 is a selective β-Catenin/T-cell factor protein-protein interaction (β-catenin/Tcf PPI) inhibitor. β-catenin-IN-37 inhibits canonical Wnt signaling and the growth of colorectal cancer cells SW480 and HCT116 with the IC 50 values of 20 μM and 31 μM, respectively.
CAS:
1783856-40-5
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Catrow JL, et al. Discovery of Selective Small-Molecule Inhibitors for the ?-Catenin/T-Cell Factor Protein-Protein Interaction through the Optimization of the Acyl Hydrazone Moiety. J Med Chem. 2015;58(11):4678-4692.