MY33-3
| Code | Size | Price |
|---|
| TAR-T39677-5mg | 5mg | £284.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
MY33-3 is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ , with an IC 50 of ~0.1 μM. MY33-3 also inhibits PTP-1B ( IC 50 ~0.7 μM). MY33-3 can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction.
CAS:
2204280-41-9
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Fern?ndez-Calle R, et, al. Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase ?/? (PTPRZ1) modulates behavioral responses to ethanol. Neuropharmacology. 2018 Jul 15;137:86-95.
Mao S, et, al. Pleiotrophin Potentiates Sevoflurane Anesthesia-induced Learning Deficits in Mice. J Mol Neurosci. 2022 Jan;72(1):48-55.
Fern?ndez-Calle R, et, al. Role of RPTP?/? in neuroinflammation and microglia-neuron communication. Sci Rep. 2020 Nov 20;10(1):20259.